ESPCI web site
- method based on the distribution of compounds between a stationary phase (selected sorbent) and a liquid phase (sample)
Principe de l’extraction sur phase solide :
- Conditionnement du support
- Percolation de l’échantillon : si le soluté présente une forte affinité vis à vis de l’adsorbant, il reste totalement fixé sur celui-ci
- Une étape de lavage est ensuite réalisée pour éliminer les interférents sans en affecter la rétention du composé sur le support
- Elution du soluté par un faible volume d’un solvant éluant par rupture des interactions solutés-adsorbant
Research axes :
- Model of the retention process using the strong analogy between SPE and elution chromatography
- Evaluation of SPE sorbents and optimization of SPE procedure of trace analysis
- On-line SPE-liquid chromatography coupling and its miniaturization
Recent Collaborations/project: ANR BMAALS (2011-2015)
Recent publication:
Validation of the analytical procedure for the determination of the neurotoxin β-N-methylamino-L-alanine in complex environmental samples, A. Combès, et al. Anal Chim. Acta 2013, 771, 42-49
Highlights :
- Organization of professional training for technicians or engineers from the French industry or from public institutes in Sample treatment in trace analysis of organic compounds
- Participation to the scientific committee of the Internal Symposium on Sample Treatment (Extech, HSTP-HTC series)
