Laboratoire Sciences, Bioanalytiques et Miniaturisation : Electrophoresis on chip

Electrophoresis on chip

Transfer to chip format of new electrokinetic methods developped first in classical capillary format to save time and money, such as an example for affinity measurement of biomolecules bonded on nanoparticules

Development of miniaturized bioanalytical methods.
Example: Soludiag ANR – Method development for the diagnostic of allergy by ELISA tests involving nanoparticules bonded with allergens and integrated in a microfluidic microsystem

In situ synthesis of monolithic stationary phases for preconcentration and electrochromatographic separation

Collaborations : MMN ESPCI ParisTech (Dir. Prof. Tabeling)

Publications:

Versatile method for electroosmotic flow measurement in microchip electrophoresis, Y. Shakalisava et al, J. Chromatogr. A 1216 (2009) 1030-1033
Integrated microdevice for preconcentration and separation of a wide variety of compounds by electrochromatography, G. Proczek et al, Electrophoresis 30 (2009) 515-524

– Goal : Developing high performance and mass production compatible columns taking advantage of the specificity offered by the columns on chip (...)

Synthesis and characterization of molecularly imprinted polymers (MIP) produced in situ as monolith in a 100 µm-diameter capillary and coupled (...)

The laboratory