Research objectives of analytical chemists are strongly dependant on asks from the society. In many areas (health, drug design, food safety, environment) the common needs are the development of rapid methods, with low costs, easy to use on the field or in vivo, environmentally friendly (low amount of organic solvent) that can be handled from very low amount of sample (drop of blood or less). There is also a need for solving very complex samples (proteomics, natural products, petroleum products) and for trace and ultra-trace analysis in complex samples.

In order to answer to these demands, the "Analytical and Bioanalytical Sciences and Miniaturization" team headed by Prof. V. Pichon has focussed its research on the development of multidimensional chromatographic modes for solving complex samples and on the development of highly selective extraction sorbents for trace analysis. Miniaturization has been also considered as an answer to rapid analysis from low amount of samples with development of fully integrated nanoliquid chromatography based methods but also electrokinetic and gas chromatography on chip.

Publications marquantes

  • A. Enel, J. Vial, D. Thiébaut, B. Bourlon : Gas digital microfluidic platform : Application to highly volatile compound reconcentration, Analytical Chemistry, March 2022, vol. 94, issue 10, p. 4359-4365 10.1021/acs.analchem.1c05128
  • P. Kadhirvel, A. Combes, L. Bordron, V. Pichon : Development and application of water-compatible molecularly imprinted polymers for the selective extraction of carbamazepine from environmental waters, A. and B. C., March 2019, vol. 411, issue 8, p. 1525-1536 10.1007/s00216-019-01586-8
  • J. Campéri, V. Pichon, T. Fournier, N. Delaunay : First profiling in hydrophilic interaction liquid chromatography of intact human chorionic gonadotropin isoforms, JPBA, 2019, Sept. 2019, vol 174, p. 495-499, 10.1016/j.jpba.2019.06.014
  • O. Petkovic, P. Guibal, P. Sassiat, J. Vial, D. Thiébaut : Active modulation in neat carbon dioxide packed column comprehensive two-dimensional supercritical fluid chromatography, J. Chrom. A, 2018, vol. 1536, p. 176-184, 10.1016/j.chroma.2017.08.063
  • M. Moussa, M. M. Ndiaye, T. Pinta, V. Pichon, T. Vercouter, N. Delaunay : Selective solid phase extraction of lanthanides from tap and river waters with ion imprinted polymers, Analytica Chimica Acta 2017, 963, p. 44-52
  • M. Bonichon, A. Combès, C. Desoubries, A. Bossé, V. Pichon : Development of immobilized-pepsin microreactors coupled to nano liquid chromatography and tandem mass spectrometry for the quantitative analysis of human butyrylcholinesterase, J.Chrom. A, Août 2016, vol 1461, p. 84-91 doi:10.1016/j.chroma.2016.07.058.

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Practical information

Headmistress : Pr. Valérie Pichon
email : valerie.pichon (arobase) espci.fr
CBI’s Administrator : Isabelle Borsenberger +33 (0)1 40 79 46 35
Administrator Assistant : Hélène Dodier +33 (0)1 40 79 46 35