Selective SPE sorbents

Principle: use of a sorbent that allows the selective trapping of target analytes without retaining other matrix components in order to facilitate and to improve the reliability of the analytical method

Example:
Analysis of triazines in a soil extract (obtained by solvent extraction) with or without a purification on a selective sorbent allowing the extraction of three triazines (1. atrazine, 2. simazine, 3. terbutylazine)

Developed sorbents :

  • Immunosorbents : based on antibodies covalently immobilized on a solid phase
  • Molecularly imprinted polymers (MIP) : polymeric sorbent containing specific cavities obtained by radical polymerization or by a Sol-Gel approach
  • Oligosorbents based on aptamers (DNA or RNA single strands selected for their high specificity for a target compound) covalently immobilized on a solid phase

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See also...

Electrokinetic preconcentration

The miniaturized separation techniques suffer from a lack of sensitivity, due to the low injected sample amount and/or weak optical path-length (...) 

> More...

Immunosorbents

These are solid sorbent (silica particles, agarose gel, monolith…) covalently grafted by antibodies specific of a molecule or of a group of (...) 

> More...

 


Practical information

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