Principle: use of a sorbent that allows the selective trapping of target analytes without retaining other matrix components in order to facilitate and to improve the reliability of the analytical method
Example:
Analysis of triazines in a soil extract (obtained by solvent extraction) with or without a purification on a selective sorbent allowing the extraction of three triazines (1. atrazine, 2. simazine, 3. terbutylazine)
Developed sorbents :
- Immunosorbents : based on antibodies covalently immobilized on a solid phase
- Molecularly imprinted polymers (MIP) : polymeric sorbent containing specific cavities obtained by radical polymerization or by a Sol-Gel approach
- Oligosorbents based on aptamers (DNA or RNA single strands selected for their high specificity for a target compound) covalently immobilized on a solid phase